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Krstovski N et al. - The findings as well as previously reported data, contributes to a hypothesis of different biology and etiology of adult and childhood AML. More extensive studies of NPM1 and FLT3 mutations in childhood AML are needed to determine their biological and clinical importance.

Today in Basic Science/Genetics...keeping you current

Thrombopoietin in normal and neoplastic stem cell development
Best Practice & Research: Clinical Haematology , 12/07/09

Mechanisms of mutations in myeloproliferative neoplasms
Best Practice & Research: Clinical Haematology , 12/07/09

Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma
International Journal of Cancer, 12/07/09