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New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells
Cancer Science, 07/01/09
Lin L et al. - The results indicate that FLLL11 and FLLL12 exhibit more potent activities than curcumin on the inhibition of STAT3, AKT, and HER-2/neu, as well as inhibit cancer cell growth and migration, and may thus have translational potential as chemopreventive or therapeutic agents for breast and prostate cancers.
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Today in Basic Science/Genetics...keeping you current
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Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia
Haematologica, 12/20/09
The mitogen-activated protein kinase signaling pathways: role in megakaryocyte differentiation
Journal of Thrombosis and Haemostasis, 12/20/09
Reprogramming T Lymphocytes for Melanoma Adoptive Immunotherapy by T-Cell Receptor Gene Transfer with Lentiviral Vectors
Cancer Research, 12/20/09
Today in Breast...keeping you current
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The risk for breast cancer is not evidently increased in women with hyperprolactinemia
Pituitary, 12/20/09
Extracellular Signal–Regulated Kinase Signaling Pathway Regulates Breast Cancer Cell Migration by Maintaining slug Expression
Cancer Research, 12/20/09
Screening for Founder Mutations in BRCA1 and BRCA2 in Unselected Jewish Women
Journal of Clinical Oncology, 12/19/09
Today in Renal/Urologic...keeping you current
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Papillary renal cell carcinoma with diffuse clear cells and thyroid-like macrofollicular areas
Annals of Diagnostic Pathology, 12/20/09
High DNA Methyltransferase 3B Expression Mediates 5-Aza-Deoxycytidine Hypersensitivity in Testicular Germ Cell Tumors
Cancer Research, 12/19/09
Testing the Circadian Gene Hypothesis in Prostate Cancer: A Population-Based Case-Control Study
Cancer Research, 12/19/09
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