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Abnormal centrosome-centriole cycle in chronic myeloid leukaemia
British Journal of Haematology, 06/29/09
Patel H et al. - Levels of the protease, separase are abnormally high in CML CP and BC cells in comparison to normal CD34+ cells. The data imply that expression of p210BCR-ABL1 is associated with abnormalities in the centrosome-centriole cycle and increased separase expression.
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