Oncology Medical News about myeloid differentiation

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Reintroduction of CEBPA in MN1-overexpressing hematopoietic cells prevents their hyper proliferation and restores myeloid differentiation
Blood, 06/29/09

Kandilci A et al. - Re-introduction of conditional and constitutive CEBPA overcame the effects of MN1 on myeloid differentiation and inhibited MN1-induced proliferation in vitro. These results indicate that down regulation of CEBPA activity contributes to MN1-modulated proliferation and impaired myeloid differentiation of hematopoietic cells.

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JunB Protects against Myeloid Malignancies by Limiting Hematopoietic Stem Cell Proliferation and Differentiation without Affecting Self-Renewal
Cancer Cell, 10/01/09 Relevance Score: 68%%

SUZ12 is a candidate target of the non-canonical WNT pathway in the progression of chronic myeloid leukemia
Genes, Chromosomes and Cancer, 10/28/09 Relevance Score: 67%%

PU.1 Activation Relieves GATA-1–Mediated Repression of Cebpa and Cbfb during Leukemia Differentiation
Molecular Cancer Research, 10/20/09 Relevance Score: 65%%

Soluble Triggering Receptor Expressed on Myeloid Cells-1 Is an Early Marker of Infection in the Surgical Intensive Care Unit
Surgical Infections, 10/06/09 Relevance Score: 65%%

Increased frequencies of T helper type 17 cells in the peripheral blood of patients with acute myeloid leukaemia
Clinical and Experimental Immunology, 10/05/09 Relevance Score: 64%%