Your Article Summary
See Latest ArticlesCytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis from colorectal and gastrointestinal origin shows acceptable morbidity and high survival
European Journal of Surgical Oncology, 07/01/09
Hagendoorn J et al. - In a study to examine the use of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with peritoneal carcinomatosis of colorectal and gastrointestinal origin, it was concluded that in well-selected pts referred to a specialized institution, CS–HIPEC has acceptable morbidity and high survival rate.
Methods- 67 pts underwent a laparotomy.
- Complete cytoreduction could be performed in 49 pts, who underwent 53 CS–HIPEC procedures.
- All had peritoneal carcinomatosis originating from primary colorectal, cecal, appendiceal, and gastric tumors.
- In pts who underwent CS–HIPEC, an R0 resection could be achieved in 4%, R1 in 88%, and R2 in 8%.
- 30-day mortality was 0; 1 pt died in-hospital after 10 wks.
- Median hospital stay was 12 days.
- Overall morbidity was 43%, including extended gastroparesis (11%), anastomotic failure (11%), and intra-abdominal abscess (9%).
- Mean time to clinical recurrence was 12 mos.
- Actuarial 1-yr survival was 88% and 2-yr survival was 75%.
Related Articles
Combined chemotherapy with carboplatin plus irinotecan showed favorable efficacy in a patient with relapsed small cell carcinoma of the prostate complicated with meningeal carcinomatosis
International Journal of Clinical Oncology, 10/30/09
Relevance Score: 84%
KAP1 Is Associated With Peritoneal Carcinomatosis in Gastric Cancer
Annals of Surgical Oncology, 11/11/09
Relevance Score: 83%
Peritoneal carcinomatosis and liver metastases from colorectal cancer treated with cytoreductive surgery perioperative intraperitoneal chemotherapy and liver resection
European Journal of Surgical Oncology, 11/17/09
Relevance Score: 80%
Noninternalizing Monoclonal Antibodies Are Suitable Candidates for 125I Radioimmunotherapy of Small-Volume Peritoneal Carcinomatosis
The Journal of Nuclear Medicine, 11/16/09
Relevance Score: 80%
Peritoneal carcinomatosis from ovarian cancer: the role of CT and [18F]FDG-PET/CT
Abdominal Imaging, 10/01/09
Relevance Score: 80%
Today in Colorectal Cancer/Polyps...keeping you current
Receive free subspecialty "5-minute updates" via email
EORTC Elderly Task Force experts opinion for the treatment of colon cancer in older patients
Cancer Treatment Reviews, 12/04/09
Absolute benefits of medical therapies in phase III clinical trials for breast and colorectal cancer
Annals of Oncology, 12/04/09
Bevacizumab combined with chemotherapy for patients with advanced colorectal cancer: a systematic review
Annals of Oncology, 12/04/09
Today in GI Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
ML17032 trial: capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in advanced gastric cancer
Expert Review of Anticancer Therapy, 12/04/09
Clinical implications of esophagorespiratory fistulae in patients with esophageal squamous cell carcinoma (SCCA)
Medical Oncology, 12/04/09
Clinicopathological characteristics of primary gastric T-cell lymphoma
Histopathology, 12/04/09