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Liver perfusion with dynamic multidetector-row computed tomography as an objective method to evaluate the efficacy of chemotherapy in patients with colorectal cancer
Clinical Imaging, 06/30/09

Pauls S et al. - In a study to evaluate the use of liver perfusion with dynamic multidetector-row computed tomography as an objective method to evaluate efficacy of chemotherapy in pts with colorectal cancer (CRC), it appears that CT is able to quantify perfusion and local activity of liver metastases to determine the efficacy of chemotherapy.

Methods

24 liver metastases of CRC were evaluated by dynamic multiphasic CT.
Under chemotherapy, follow-up examinations were performed every 3 mos.

Results

Tumor marker CEA before vs after chemotherapy correlated with the mean contrast enhancement within the margin of metastases.
The total size of metastases correlated with size of central necrosis as well as with size of marginal contrast enhancement.

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Colorectal cancer incidence and postmenopausal hormone use by type, recency, and duration in cancer prevention study II
Cancer Epidemiology, Biomarkers & Prevention, 10/28/09 Relevance Score: 72%

Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk
Cancer Causes and Control, 10/02/09 Relevance Score: 72%

P73 expression and its clinical significance in colorectal cancer
Colorectal Disease, 10/19/09 Relevance Score: 71%

trans-Fatty acid consumption and its association with distal colorectal cancer in the North Carolina Colon Cancer Study II
Cancer Causes and Control, 10/28/09 Relevance Score: 70%

Association of clinicopathological features with UbcH10 expression in colorectal cancer
Journal of Cancer Research & Clinical Oncology, 10/01/09 Relevance Score: 70%