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An update on long-term outcome of curative hepatic resection for hepatocholangiocarcinoma
World Journal of Surgery, 06/29/09

Chok KSH et al. - Hepatocholangiocarcinoma (HCC-CC) entails poor long-term outcome after potentially curative hepatectomy. Other modalities of treatment should be explored in order to prolong survival of patients with this disease.

• A review of the long-term outcome of curative hepatectomy for HCC-CC
• Prospectively collected data from Dec 1991-2006 recording pts with primary liver cancer receiving curative hepatectomy
• 25 pts, 16 men; median age: 48 yrs; all ethnic Chinese, had HCC-CC
• Their long-term outcome of resection was analyzed and compared to that of pts with cholangiocarcinoma (CC) or hepatocellular carcinoma (HCC)

• HCC-CC pts had a median tumor size of 7.5 cm
• 5 of them developed postoperative complications
• Median f/u period was 25 mo; all pts developed recurrence
• Median overall survival was 25.2 mo; HCC-CC and CC groups had worse overall survival than HCC group
• Whereas between them there was no significant difference
• As for disease-free survival, there was no significant difference between the 3 groups:
  • For HCC-CC pts: 13.5 mo
  • CC pts: 16.1 mo, and
  • HCC pts: 19.0 mo
• All HCC-CC pts died within 120 mo of primary surgery

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