Oncology Medical News about sickle erythrocyte subpopulations

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Aminophospholipid translocase and phospholipid scramblase activities in sickle erythrocyte subpopulations
British Journal of Haematology, 06/26/09

Barber LA et al. - The findings indicate that (i) PS externalization in mature sickle RBC depends on the balance between APLT and PLSCR activities, (ii) PS externalization in sickle reticulocytes depends primarily on PLSCR activation and (iii) APLT inhibition in sickle RBC dehydrated in vivo is due to dehydration itself and other factors.

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