Oncology Medical News about hepatocarcinogenesis

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Bile ductular cell reaction with senescent hepatocytes in chronic viral hepatitis is lost during hepatocarcinogenesis
Pathology International, 06/26/09

Ikeda H et al. - Loss of a complex of senescent hepatocytes and ductular cell including hepatic progenitor-like cells in the periportal or periseptal areas may be associated with emergence of neoplastic hepatocytes and their proliferation followed by neoplastic nodules arising in liver cirrhosis. Zonal proliferation of CK7-positive small neoplastic hepatocytes resembling hepatic progenitor cells may develop during early hepatocarcinogenesis.

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Activity of sulfotransferase 1A1 is dramatically upregulated in patients with hepatocellular carcinoma secondary to chronic hepatitis B virus infection
Cancer Science, 11/17/09 Relevance Score: 80%

MiR-122 affects the viability and apoptosis of hepatocellular carcinoma cells
Scandinavian Journal of Gastroenterology, 11/06/09 Relevance Score: 80%

Interaction between cytochrome P450 1A2 genetic polymorphism and cigarette smoking on the risk of hepatocellular carcinoma in a Japanese population
Carcinogenesis, 10/08/09 Relevance Score: 80%