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See Latest ArticlesImpact of menopausal symptoms on quality of life 6 months after systemic breast cancer treatment: results from the Shanghai Breast Cancer Survival Study
Breast Cancer Research and Treatment, 06/24/09
Dorjgochoo T et al. - In a study to assess whether menopausal symptoms (MPS) affect health-related quality of life (QOL) in Asian women with breast cancer, it was suggested that in Chinese women recently treated for breast cancer, MPS adversely impacts QOL. Actively soliciting and treating MPS in these women should significantly improve their QOL.
Methods- QOL was assessed by using the generic quality of life instruments, Medical Outcome Study of Quality of Life Inventory (MOSQOL-74) or Short Form-36 Health Survey (SF-36) in 4976 Chinese participants who were treated for incident, non-metastatic breast cancer within the 6 mos before study interview.
- Relationships between MPS and QOL were assessed by multiple linear regression, controlling for potential confounders.
- About 71.4% of study participants experienced MPS, including hot flashes, night sweats, vaginal dryness, depressed mood, and/or dry skin.
- Women with MPS reported lower overall QOL than women without MPS.
- Adjusted mean differences (β) in overall QOL in the presence and absence of MPS were -3.1 with the MOSQOL-74 and -12.3 with the SF-36.
- Women with any MPS had lower scores for the MOSQOL-74 physical and psychological domains and for the SF-36 social and emotional subscales than those without MPS.
- Having several MPS predicted poorer QOL in all domains measured regardless of the instrument used.
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