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See Latest ArticlesRevisiting the role of positron-emission tomography/computed tomography in determining the need for planned neck dissection following chemoradiation for advanced head and neck cancer
The Laryngoscope, 06/25/09
Gourin CG et al. - In a study to assess the use of positron-emission tomography/computed tomography (PET-CT) in identifying occult nodal disease for planned neck dissection following chemoradiation for advanced head and neck squamous cell cancer (HNSCC), the data suggest that delaying the timing of PET-CT, with surgery reserved for positive findings, is a reasonable alternative to planned neck dissection to avoid unnecessary surgery.
Methods- Medical records of all pts treated with chemoradiation (CR) for advanced HNSCC with N2 or N3 disease were reviewed.
- Pts with a complete clinical response were included if PET-CT performed 8 to 11 wks after CR showed no distant disease and they underwent planned neck dissection.
- 32 pts met study criteria.
- PET-CT was positive for residual nodal disease in 20 pts (63%).
- Pathology revealed carcinoma in 10 pts (31%): 6 of 20 pts with positive PET-CT scans (30%) and 4 of 12 pts with negative PET-CT scans (33%).
- Sensitivity and specificity of PET-CT was 60% and 36%.
- Regional recurrence developed in 2 pts (6%) who were not successfully salvaged.
Today in Diagnostics/Radiology...keeping you current
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Risk of dying from prostate cancer in men randomized to screening
Cancer, 10/13/09
Early PSA decrease is an independent predictive factor of clinical failure and specific survival in patients with localized prostate cancer treated by radiotherapy with or without androgen deprivation therapy
Annals of Oncology, 10/16/09
Potential predictive markers of chemotherapy resistance in stage III ovarian serous carcinomas
BMC Cancer, 10/21/09
Today in Head and Neck...keeping you current
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Mobile Phone Use and Risk of Tumors: A Meta-Analysis
Journal of Clinical Oncology, 10/20/09
Thyroid lymphoma and airway obstruction – is there a rationale for surgical management?
International Journal of Clinical Practice, 10/19/09
Primary extranodal marginal zone lymphoma of the uvea associated with massive diffuse epibulbar extension and focal infiltration of the optic nerve and meninges, clinically presented as uveitis masquerade syndrome: a case report
Medical Oncology, 10/16/09
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