Oncology Medical News about Breast

Your Article Summary

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Diffusion-weighted imaging of mucinous carcinoma of the breast
American Journal of Roentgenology, 06/29/09

Woodhams R et al. - Study demonstrates that mucinous carcinoma can be clearly differentiated from other breast tumors on the basis of apparent diffusion coefficient (ADC). The low and high signal intensity of mucinous carcinoma on diffusion-weighted images reflects distinct features.

Methods

Objectives of this study were to:
- Compare ADC of mucinous carcinoma of the breast with that of other breast tumors, and
- Analyze correlations between signal intensity on diffusion-weighted images and the histologic features of mucinous carcinoma
276 pts with 277 lesions, including:
- 15 mucinous carcinomas (13 pure type, 2 mixed type)
- 204 other malignant tumors, and
- 58 benign lesions
  were examined with 1.5-T MRI at b values of 0 and 1,500 s/mm²
Correlations between cellularity and ADC, homogeneity of signal intensity on diffusion-weighted images, and histopathologic findings were analyzed

Results

Mean ADC of mucinous carcinoma was higher than that of benign lesions and other malignant tumors
ADC of pure type mucinous carcinoma was higher than that of mixed type mucinous carcinoma and other histologic types
Correlation between mean cellularity and ADC of mucinous carcinoma was significant
Homogeneity of signal intensity on diffusion-weighted images correlated with the homogeneity of histologic structures

<< Previous
Combined effects of obesity and type 2 diabetes contribute to...

Next >>
Four-year clinical update from the American Society of Breast...

Contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers
Journal of Clinical Oncology, 10/29/09 Relevance Score: 97%

New-Onset Breast Tenderness After Initiation of Estrogen Plus Progestin Therapy and Breast Cancer Risk
Archives of Internal Medicine, 10/13/09 Relevance Score: 97%

Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: The UK MARIBS study
Breast Cancer Research, 11/17/09 Relevance Score: 96%

Breast-feeding the last born child and risk of ovarian cancer
Cancer Causes and Control, 11/16/09 Relevance Score: 96%

Novel breast tissue feature strongly associated with risk of breast cancer
Journal of Clinical Oncology, 10/08/09 Relevance Score: 96%