Your Article Summary
See Latest ArticlesEndothelin-Converting Enzyme-2 Is Increased in Alzheimer's Disease and Up-Regulated by A beta
American Journal of Pathology, 06/23/09
Palmer JC et al. - ECE-2 expression is up-regulated, perhaps to minimize A beta accumulation, but this may also be a mechanism through which endothelin-1 production is increased and cerebral blood flow is reduced in AD. The findings suggest that endothelin-1 receptor antagonists, already licensed for treating other diseases, could be of benefit in AD therapies.
Related Articles
Does Diabetes Speed Up Memory Loss In Alzheimers Disease?
ScienceDaily, 10/28/09
Relevance Score: 70%
Activated astrocytes: a therapeutic target in Alzheimer's disease?
Expert Review of Neurotherapeutics, 11/19/09
Relevance Score: 69%
High Blood Pressure Likely in Alzheimers Offspring
MedLinePlus, 11/04/09
Relevance Score: 69%
New Cause for Alzheimer Disease
ScienceDaily, 11/30/09
Relevance Score: 68%
Protective Role For Copper In Alzheimers Disease
ScienceDaily, 10/14/09
Relevance Score: 68%
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma
Clinical Cancer Research, 12/11/09
Analysis of VHL Gene Alterations and their Relationship to Clinical Parameters in Sporadic Conventional Renal Cell Carcinoma
Clinical Cancer Research, 12/11/09
Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation
British Journal of Haematology, 12/11/09
Today in Neurologic Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology
Cancer Research, 12/11/09
Glioblastoma Proto-oncogene SEC61gamma Is Required for Tumor Cell Survival and Response to Endoplasmic Reticulum Stress
Cancer Research, 12/11/09
Time Trends in Brain Tumor Incidence Rates in Denmark, Finland, Norway, and Sweden, 1974–2003
Journal of the National Cancer Institute, 12/10/09