Oncology Medical News about tumorigenesis

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Expression profiling of ependymomas unravels localization and tumor grade-specific tumorigenesis
Cancer, 07/01/09

Palm T et al. - The tumor localization-related gene sets mainly implicated in stem cell maintenance, renewal, and differentiation suggest the dysregulation of localized cancer stem cells during ependymoma development. The WHO grade differentiating pathways suggested that alteration of the Wnt beta/-catenin signaling pathway is a key event in the tumorigenesis of WHO grade 3 ependymomas.

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Pulmonary neuroendocrine/carcinoid tumors

APC promoter hypermethylation is an early event in endometrial tumorigenesis
Cancer Science, 11/16/09 Relevance Score: 88%

RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1
Oncogene, 10/26/09 Relevance Score: 88%

Induction and Down-regulation of Sox17 and Its Possible Roles During the Course of Gastrointestinal Tumorigenesis
Gastroenterology, 10/07/09 Relevance Score: 88%

Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy
Journal of Hematology & Oncology, 10/30/09 Relevance Score: 85%

High Expression of the PAX3-FKHR Oncoprotein Is Required to Promote Tumorigenesis of Human Myoblasts
American Journal of Pathology, 11/09/09 Relevance Score: 83%