Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials 4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 5. Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ
Top Ten Searches
brca1 prostate-specific antigen sclc fobt egd bmi dysplasia hematologic ovarian hccYour Article Summary
See Latest ArticlesHealth-related quality of life as a survival predictor for patients with localized head and neck cancer treated with radiation therapy
Journal of Clinical Oncology, 06/22/09
Meyer F et al. - Findings indicate that both baseline physical functioning (PF) and PF change provide added prognostic value for overall survival (OS) beyond established predictors in patients with head and neck cancer (HNC). Assessing health-related quality of life (HRQOL) could help better predict survival of cancer patients.
Methods- Aim was to assess the added prognostic value for OS of baseline HRQOL and of early changes in HRQOL among pts with localized HNC treated with radiation therapy
- 540 pts completed 2 HRQOL instruments before radiation therapy:
- European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire C30 (EORTC QLQ-C30) and
- Head and Neck Radiotherapy Questionnaire
- 6 mo after the end of radiation therapy, 497 trial participants again completed the 2 HRQOL instruments
- During the f/u, 179 deaths were observed
- Multivariate Cox proportional hazards models were used to test whether HRQOL variables, baseline and change, provided additional prognostic value
- Baseline EORTC QLQ-C30 PF score was an independent predictor of OS
- Hazard ratio (HR) associated with a 10-point increment in baseline PF was 0.87
- Multivariate models: change in HRQOL was significantly associated with OS for most HRQOL dimensions
- Among these, PF change was the strongest predictor
- Magnitude of the association between PF change and survival decreased over time
- At 1 yr, the HR associated with a positive PF change of 10 points was 0.75
- After PF is taken into account, no other HRQOL variable was associated with survival
Today in Diagnostics/Radiology...keeping you current
Receive free subspecialty "5-minute updates" via email
Risk of dying from prostate cancer in men randomized to screening
Cancer, 10/13/09
Early PSA decrease is an independent predictive factor of clinical failure and specific survival in patients with localized prostate cancer treated by radiotherapy with or without androgen deprivation therapy
Annals of Oncology, 10/16/09
Potential predictive markers of chemotherapy resistance in stage III ovarian serous carcinomas
BMC Cancer, 10/21/09
Today in Head and Neck...keeping you current
Receive free subspecialty "5-minute updates" via email
Mobile Phone Use and Risk of Tumors: A Meta-Analysis
Journal of Clinical Oncology, 10/20/09
Thyroid lymphoma and airway obstruction – is there a rationale for surgical management?
International Journal of Clinical Practice, 10/19/09
Primary extranodal marginal zone lymphoma of the uvea associated with massive diffuse epibulbar extension and focal infiltration of the optic nerve and meninges, clinically presented as uveitis masquerade syndrome: a case report
Medical Oncology, 10/16/09
Sponsor
Article Search
Sponsor
Sponsor