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Estrogen-Related Receptor Expression and Function Is Associated with the Transcriptional Coregulator AIB1 in Breast Carcinoma
Cancer Research, 06/25/09
Heck S et al. - The findings identify AIB1 as functionally relevant cofactor for ERR alpha in breast carcinoma. ERR alpha/AIB1 complexes may control estradiol-regulated genes in a hormone-independent manner. Accordingly, ERR alpha might be a rewarding target for treatment of endocrine-resistant tumors.
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Today in Basic Science/Genetics...keeping you current
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BAALC is an important predictor of refractoriness to chemotherapy and poor survival in intermediate-risk acute myeloid leukemia (AML)
Annals of Hematology, 12/01/09
In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer
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