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Chemotherapy administration during pelvic radiation for cervical cancer patients aged ≥ 55 years in the seer-medicare population
Journal of Oncology, 06/11/09
Kunos C et al. - In a trial to evaluate whether 1999 National Cancer Institute (NCI) chemoradiation guidelines for cervical cancer impacted treatment of women ≥55 yrs, it was shown that while SEER-Medicare data indicated an increasing trend for chemoradiation after the 1999 NCI clinical alert, chemoradiation was less frequent in elderly women with cervical cancer.
Methods- 385 women were identified ≥55 yrs diagnosed with stage II-IVA cervical cancer between January, 1998 and December, 2002 in the Surveillance, Epidemiology, and End Results (SEER)-Medicare registries.
- Chemoradiation frequency tables were constructed for age, race, community setting, socioeconomic status, and comorbidity index.
- Of 385 women, 166 (43%) received chemoradiation as primary treatment.
- Prior to the 1999 NCI clinical alert, 5/43 (12%) in 1998 and 24/54 (44%) in 1999 received chemoradiation.
- The chemoradiation proportion was 41% (36/87) in 2000, 48% (51/107) in 2001, and 53% (50/94) in 2002.
- Women ≥71 yrs had significantly lower odds of chemoradiation.
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