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See Latest ArticlesEffect of staurosporine on the mobility and invasiveness of lung adenocarcinoma A549 cells: an in vitro study
BMC Cancer, 06/10/09
Wang Y et al. - The study demonstrates that staurosporine inhibits cell adhesion, mobility, and invasion of A549 cells. The staurosporine-mediated inhibition of PKC-alpha, induction of E-Cad expression, and decreased integrin beta1, LnR, MMP-9, and uPA levels could all possibly contribute to this biological process. These results represent a significant step forward in the ongoing effort to understand the development of lung carcinoma and to design novel strategies to inhibit metastasis of the tumor by targeting the cell-adhesion, mobility and invasion of tumor cells.
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Today in Basic Science/Genetics...keeping you current
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Mutation analysis of the MSMB gene in familial prostate cancer
British Journal of Cancer, 12/10/09
Influence of omega-6 PUFA arachidonic acid and bone marrow adipocytes on metastatic spread from prostate cancer
British Journal of Cancer, 12/10/09
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Today in Lung/Thoracic Oncology...keeping you current
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18FDG-PET-CT in the follow-up of non-small cell lung cancer patients after radical radiotherapy with or without chemotherapy: An economic evaluation
European Journal of Cancer, 12/10/09
Stage I nonsmall cell lung cancer in patients aged >=75 years
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