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See Latest ArticlesA Novel Sulindac Derivative That Does Not Inhibit Cyclooxygenases but Potently Inhibits Colon Tumor Cell Growth and Induces Apoptosis with Antitumor Activity
Cancer Prevention Research, 06/12/09
Piazza GA et al. - The results indicate that SSA has potential safety and efficacy advantages for colon cancer chemoprevention as well as utility for treating malignant disease if combined with chemotherapy.
Gary A. Piazza, 06/12/09
| The results described in this manuscript provide strong evidence that the antineoplastic properties of NSAIDs involve a cyclooxygenase-independent mechanism. The challenge for future research will be to define this mechanism, which appears to be highly selective for tumor cells. Additionally, the studies suggest that it is possible to develop highly efficiacious and selective new drugs for cancer chemoprevention. |
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Today in Basic Science/Genetics...keeping you current
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Thrombopoietin in normal and neoplastic stem cell development
Best Practice & Research: Clinical Haematology , 12/07/09
Mechanisms of mutations in myeloproliferative neoplasms
Best Practice & Research: Clinical Haematology , 12/07/09
Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma
International Journal of Cancer, 12/07/09
Today in Colorectal Cancer/Polyps...keeping you current
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Radiotherapy in the Treatment of Resectable Rectal Adenocarcinoma
American Journal of Clinical Oncology, 12/07/09
Metastatic colorectal cancer: recent advances in its clinical management
Expert Review of Anticancer Therapy, 12/07/09
Area of residual tumor beyond the muscular layer is a useful predictor of outcome in rectal cancer patients who receive preoperative chemoradiotherapy
Pathology International, 12/07/09
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