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See Latest ArticlesClinical features of the most common fusion genes in childhood acute lymphoblastic leukemia
Medical Oncology, 06/05/09
Lazic J et al. - In a study to explore clinical features of the most common fusion genes in childhood acute lymphoblastic leukemia (ALL), study results offered additional evidence of variable incidence and clinical characteristics of ALL subtypes.
Methods- The study enrolled 70 pediatric pts with de novo ALL, analyzed using reverse transcriptase-polymerase chain reaction for the presence of 4 major risk-stratifying translocations (BCR/ABL, MLL/AF4, TEL/AML1, and E2A/PBX1).
- Bone marrow samples were collected at diagnosis, at the end of induction phase, and after intensive chemotherapy in order to establish a correlation between chromosomal aberration, clinical features, and treatment response.
- The results of this study offer more evidence of variable incidence and clinical characteristics of ALL subtypes.
Today in Basic Science/Genetics...keeping you current
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Today in Leukemia/Lymphoma...keeping you current
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Lymphoma in patients treated with anti-TNF. Results of the 3-year prospective French RATIO registry.
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Young adults with acute lymphoblastic leukemia have an excellent outcome with chemotherapy alone and benefit from intensive postinduction treatment: a report from the childrens oncology group
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Today in Pediatric Heme/Oncology...keeping you current
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Young adults with acute lymphoblastic leukemia have an excellent outcome with chemotherapy alone and benefit from intensive postinduction treatment: a report from the childrens oncology group
Journal of Clinical Oncology, 10/12/09
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Cisplatin versus cisplatin plus doxorubicin for standard-risk hepatoblastoma
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