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Moretti D et al. - The observations suggest that calpain 3 variants can play a proapoptotic role in melanoma cells and its downregulation, as observed in highly aggressive lesions, could contribute to melanoma progression.

Today in Carcinogenesis...keeping you current

Regulating the leukaemia stem cell
Best Practice & Research: Clinical Haematology , 12/09/09

Aggressive inherited and sporadic medullary thyroid carcinomas display similar oncogenic pathways
Endocrine-Related Cancer, 12/08/09

Activation of the hedgehog-signaling pathway in human cancer and the clinical implications
Oncogene, 11/30/09

Today in Dermatologic Oncology...keeping you current

Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
Proceedings of the National Academy of Sciences of the United States of America, 12/09/09

Phase II trial of temozolomide and sorafenib in advanced melanoma patients with or without brain metastases
Clinical Cancer Research, 12/09/09

Dynamic Gene Expression Analysis Links Melanocyte Growth Arrest with Nevogenesis
Cancer Research, 12/09/09