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Kim A et al. - The data show that NDRG2 expression significantly suppresses tumor invasion by inhibiting MMP activities, which are regulated through the NF-kB signaling. Moreover, results from animal experiments provide evidence for the regulatory role of the NDRG2 gene in metastatic tumors.

Today in Carcinogenesis...keeping you current

Regulating the leukaemia stem cell
Best Practice & Research: Clinical Haematology , 12/09/09

Aggressive inherited and sporadic medullary thyroid carcinomas display similar oncogenic pathways
Endocrine-Related Cancer, 12/08/09

Activation of the hedgehog-signaling pathway in human cancer and the clinical implications
Oncogene, 11/30/09