Oncology Medical News about gynaecological cancers

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Recommendations on the use of 18F-FDG PET in oncology

3. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials

4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer

5. Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Sentinel lymph node sampling in gynaecological cancers: Techniques and clinical applications
European Journal of Surgical Oncology, 06/05/09

El-Ghobashy AE et al. - In a review to evaluate the technique and the prognostic significance of the sentinel lymph node (SLN) concept in gynaecological malignancies, the SLN procedure appears to reliably predict the metastatic status of the regional lymphatic basin in pts with vulval and cervical cancers.

Methods

A computer literature search was done to identify relevant articles on SLN biopsy in women with gynaecological cancer.
MEDLINE and EMBASE databases up to 2008 were searched for the following terms: “vulva, cervix, uterine, ovarian, neoplasm, carcinoma, lymph node metastases, sentinel node, technique, and prognosis” as medical subject headings (MeSH).
Articles selected included reviews, clinical studies, letters, comments, conference proceedings, unpublished data, and case reports.

Results

Variation in detection methods of SLN was observed among the studied literature.
Large trials have been concluded for both vulval and cervical cancers showing improved detection of SLNs with the added advantage of decreased morbidity.
Detection protocol of SLN in endometrial cancer is yet to be refined.
Less work has been observed with regards to the SLN sampling in ovarian tumours.

<< Previous
Surgical management of metastatic bone disease

Next >>
Cognitive effects of pegylated interferon in individuals with...