Your Article Summary
See Latest ArticlesCancer Incidence among Patients with Alcohol Use Disorders—Long-Term Follow-Up
Alcohol and Alcoholism , 06/11/09
Thygesen LC et al. - This study confirms the well-established association between high alcohol intake and cancer of the upper digestive tract and liver. In addition, the results indicate a significantly elevated occurrence of renal cancer, but not of breast cancer and colorectal cancer, in patients with alcohol use disorders.
Methods- Included 15,258 men and 3552 women free of cancer when attending the Copenhagen Outpatient Clinic for Alcoholics in the period from 1954 to 1992.
- The cancer incidence until 1999 of the patients and the general Danish population was obtained through linkage with the Danish Cancer Registry.
- The incidence rates were standardized (SIR) according to sex, age and calendar time.
- A total of 2145 men developed cancer compared to 1140.8 expected cases (SIR = 1.9; 95% confidence interval (CI) 1.8–2.0), while 601 women developed cancer compared to 239.1 expected cases (SIR = 2.5; 95% CI 2.3–2.7).
- Highly significant and strongly elevated incidence rates were found for cancer of the tongue, mouth, pharynx, oesophagus, liver, larynx and lung.
- A higher incidence rate was seen for renal cancer for both men (1.4; 1.1–1.8) and women (2.1; 1.0–3.8).
- The incidence of breast cancer in women was non-significantly elevated, but significantly elevated incidence rate was found for cervical cancer (1.8; 1.2–2.6).
- We did not observe increased incidence of colon, rectal or urinary bladder cancer.
Related Articles
Understanding the link between HPV and oropharyngeal cancers
JAAPA, 10/20/09
Relevance Score: 80%
The impact of changes in hormone therapy on breast cancer incidence in the US population
Cancer Causes and Control, 10/07/09
Relevance Score: 71%
Changing cancer incidence in Kampala, Uganda, 1991-2006
International Journal of Cancer, 11/10/09
Relevance Score: 70%
A prospective study of lifetime physical activity and prostate cancer incidence and mortality
British Journal of Cancer, 11/02/09
Relevance Score: 70%
Alcohol Stimulates Activation of Snail, Epidermal Growth Factor Receptor Signaling, and Biomarkers of Epithelial-Mesenchymal Transition in Colon and Breast Cancer Cells
Alcoholism, 10/29/09
Relevance Score: 70%
Today in Head and Neck...keeping you current
Receive free subspecialty "5-minute updates" via email
Effects of functional electrical stimulation on dysphagia caused by radiation therapy in patients with nasopharyngeal carcinoma
Supportive Care in Cancer, 12/09/09
The effectiveness of dexmedetomidine infusion for sedating oral cancer patients undergoing awake fibreoptic nasal intubation
European Journal of Anaesthesiology, 12/09/09
Prognostic significance of fascin-1 and E-cadherin expression in laryngeal squamous cell carcinoma
European Journal of Cancer Prevention, 12/09/09