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See Latest ArticlesSurgical management of metastatic bone disease
Journal of Bone and Joint Surgery, 06/05/09
Bickels J et al. - In a review of the surgical management of metastatic bone disease, it was concluded that detailed preoperative evaluation is required to assess the local extent of bone destruction and soft-tissue involvement, involvement of other skeletal sites, and overall medical and oncological status.
Methods- Metastatic bone disease is a major contributor to the deterioration of quality of life of pts with cancer.
- It causes pain, impending and actual pathological fractures, and loss of function and may be associated with considerable metabolic alterations.
- Operative treatment may be required for an impending or existing fracture and intractable pain.
- Goals of surgery are to provide local tumor control and allow immediate weight-bearing and function.
- Radiation therapy is often indicated postoperatively.
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Prediction model of chemotherapy response in osteosarcoma by 18F-FDG PET and MRI
The Journal of Nuclear Medicine, 08/26/09
Multidisciplinary treatment including sorafenib stabilized the bone metastases of renal cell carcinoma in an immunosuppressed renal transplant recipient
International Journal of Clinical Oncology, 10/30/09
Risk of fracture after single fraction image-guided intensity-modulated radiation therapy to spinal metastases
Journal of Clinical Oncology, 09/14/09
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