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Hypermethylated Genes as Biomarkers of Cancer in Women with Pathologic Nipple Discharge
Clinical Cancer Research, 06/03/09
Fackler MJ et al. - The positive predictive value of ductoscopy was more than doubled (19% versus 47%) with the addition of QM-MSP, demonstrating the benefit of targeting ducts having both high methylation and significant abnormalities on ductoscopy for surgical excision. Future large-scale studies to validate this approach are needed.
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