Oncology Medical News about sarcoma;small pulmonary nodules

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. Recommendations on the use of 18F-FDG PET in oncology

3. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials

4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer

5. Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Management of small pulmonary nodules in patients with sarcoma
Clinical and Experimental Metastasis, 05/28/09

Nakamura T et al. - In a study to establish management guidelines for small pulmonary nodules in pts with sarcoma, it was concluded that the only factor to diagnose in a metastatic pulmonary lesion is the size of the nodules. If the nodule remains ≤5 mm in size for >6 mos, the nodule will be a benign lesion. If the nodule becomes >5 mm within 6 mos, a surgical excision of the nodules is recommended.

Methods

Pulmonary nodules were detected in 70 of 206 pts with sarcoma.
About 55 pts were classified as having pulmonary metastasis.
17 of 55 pts with pulmonary metastases were excluded from imaging review because they did not undergo the required imaging examination.

Results

This study reviewed 38 pts with metastatic nodules and 15 pts with benign nodules.
A statistically significant relationship was observed between the size of the nodules and final clinical decision.
Pts with pulmonary nodules, which did not exceed 5 mm in size, showed significantly better cumulative overall survival (OS) rate after the detection of pulmonary nodules than those with larger nodules (5-yrs: 58.4 vs 20.4%).
There was no significant difference in the OS rate between pnts with smaller pulmonary benign lesions which did not exceed 5 mm in size and those with a normal chest CT (5-yrs: 92.3 vs 85.3%).

<< Previous
Effects of a novel DNA methyltransferase inhibitor zebularine on...

Next >>
Docetaxel enhances the cytotoxic effects of imatinib on...