Oncology Medical News about Deferasirox Therapy

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Managing Iron Overload in Patients with Myelodysplastic Syndromes with Oral Deferasirox Therapy
The Oncologist, 05/27/09

Jabbour E et al. - Adequate management of AEs and practical approaches such as patient education and counseling are necessary to ensure that patients remain compliant with therapy. Regular monitoring of serum ferritin levels is key to identifying patients who require iron chelation therapy, and to ensure maintenance of iron levels below the critical level of 1,000 µg/l. The flexible dosing regimen of deferasirox allows dose adjustments to be made in response to trends in serum ferritin, to changes in a patient's transfusional iron intake, and to the objectives of treatment, allowing the full benefit of transfusion therapy without the risks associated with iron overload.

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