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Phase II Trial of Dacarbazine and Thalidomide for the Treatment of Metastatic Melanoma
Chemotherapy, 05/19/09
Ott PA et al. - The addition of thalidomide to dacarbazine in metastatic melanoma yielded activity insufficient to proceed with additional trials of this combination. Thalidomide dose escalation beyond 200 mg/day was limited by unacceptable toxicity. Therefore, this combination does not warrant further investigation.
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