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Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q
Journal of Neuro-Oncology, 05/12/09
Aghi MK et al. - The authors found higher infection rates after glioblastoma diagnosis in patients whose tumors maintained chromosome 10q than in patients whose tumors had allelic 10q loss. Differing effects of this genetic alteration on antitumor and systemic immunity may warrant further investigation, potentially providing insight into mechanisms of antitumor immunity and host defenses against local and systemic infections.
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