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Thalidomide treatment down-regulates SDF-1alpha and CXCR4 expression in multiple myeloma patients
Leukemia Research, 05/12/09
Oliveira AM et al. - The findings indicate that thalidomide therapy induces down-regulation of CXCR4 and its ligand SDF-1alpha in multiple myeloma.
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Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs
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