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Sentinel node biopsy for follicular tumours of the thyroid gland
British Journal of Surgery, 04/20/09

Takeyama H et al. – Study shows that detection of sentinel lymph node (SLN) metastasis was helpful in diagnosing follicular thyroid cancer and thus enabling one-stage surgery.

Methods

Aim was to evaluate whether SLN biopsy is helpful in obtaining the correct diagnosis of malignant follicular-type tumours
SLN biopsy performed for 37 follicular-type tumours suspected to be malignant
It was based on preoperative examinations, but for which the diagnosis had not been confirmed

Results

SNs were identified in 32/37 procedures
SLN metastases were found in 4/12 pts with a malignant tumour identified by intraoperative frozen-section analysis
There was 1 false-negative but no false-positive diagnoses
Frozen-section analysis of the tumour itself identified only 1 follicular cancer
Accuracies of preoperative imaging methods were lower than that of SLN detection

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