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The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation
Carcinogenesis, 04/09/09
Lee NY et al. - The results imply that Pin1 amplifies insulin signaling in hepatocarcinoma cells through its interaction with p70S6K, suggesting that Pin1 plays an important role in insulin-induced tumorigenesis and is a potential therapeutic target in hepatocarcinoma.
Today in Basic Science/Genetics...keeping you current
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Serum calcium levels are elevated among women with untreated postmenopausal breast cancer
Cancer Causes and Control, 11/03/09
Circulating tumour cells early predict progression-free and overall survival in advanced colorectal cancer patients treated with chemotherapy and targeted agents
Annals of Oncology, 11/02/09
Evaluating the combined effect of comorbidity and prostate-specific antigen kinetics on the risk of death in men after prostate-specific antigen recurrence
Journal of Clinical Oncology, 11/02/09
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Antitumorigenic effects of cannabinoids beyond apoptosis
Journal of Pharmacology and Experimental Therapeutics, 11/06/09
The emerging role of the distal Fallopian tube and p53 in pelvic serous carcinogenesis
The Journal of Pathology, 11/05/09
Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis
Oncogene, 11/05/09
Today in Hepatobiliary/Pancreas...keeping you current
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Surgical management of hepatocellular carcinoma: Is the jury still out
Surgical Oncology, 11/05/09
Gemcitabine, oxaliplatin and 5-FU in advanced bile duct and gallbladder carcinoma: two parallel, multicentre phase-II trials
British Journal of Cancer, 11/13/09
Transarterial chemoembolisation (TACE) using irinotecan-loaded beads for the treatment of unresectable metastases to the liver in patients with colorectal cancer: an interim report
World Journal of Surgical Oncology, 11/09/09
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