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See Latest ArticlesThe NFATc2 Gene Is Involved in a Novel Cloned Translocation in a Ewing Sarcoma Variant That Couples Its Function in Immunology to Oncology
Clinical Cancer Research, 04/06/09
Szuhai K et al. - A new translocation involving EWSRI and NFATc2 was cloned. NFATc2 is a transcription factor that is not a member of the ETS family and functions in T-cell differentiation and immune response. Direct involvement of NFATc2 has not yet been observed in oncogenesis. The authors show that due to the shared sequence recognition of NFATc2 and the ETS family, shared transcriptional control is possible using activating protein complex 1.
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Today in Basic Science/Genetics...keeping you current
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Fas-induced apoptosis of renal cell carcinoma is mediated by apoptosis signal-regulating kinase 1 via mitochondrial damage-dependent caspase-8 activation
Cellular Oncology, 12/08/09
Cyclo-oxygenase 2 modulates chemoresistance in breast cancer cells involving NF-kappaB
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Cyclooxygenase-2 mediated regulation of E-cadherin occurs in conventional but not early-onset gastric cancer cell lines
Cellular Oncology, 12/08/09
Today in Soft Tissue/Sarcoma...keeping you current
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Angiosarcoma of the Breast: A Rare Clinicopathological Entity
American Journal of Clinical Oncology, 12/08/09
Interaction of Histologic Subtype and Histologic Grade in Predicting Survival for Soft-Tissue Sarcomas
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Surgical treatment of pelvic chondrosarcoma involving periacetabulum
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