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Osteopontin stimulates invasion of NCI-h295 cells but is not associated with survival in adrenocortical carcinoma
The Journal of Pathology, 04/08/09
Weismann D et al. - In vitro data indicate that OPN and integrin alphav beta3 may act as a functional complex facilitating the invasiveness of adrenocortical tumours. This relationship remains of relevance to authors' understanding of carcinogenesis, but further studies are needed to address the physiological and pathological function of OPN in adrenal tissue.
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