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Effects of imatinib mesylate in osteoblastogenesis
Experimental Hematology, 03/30/09
Tibullo D et al. - The data show that IM increases mRNA expression of osteogenic markers in hBM-MSCs and increases the OPG/RANKL ratio and the OCN levels both in surnatant of hBM-MSCs cultured with IM and in serum of patients treated with IM, thus indicating that IM potentially favors osteoblastogenesis.
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