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Preserving functional independence in elderly patients with cancer-associated bone disease: the role of zoledronic acid
Aging Health, 03/26/09
Major PP - In a review of the role of zoledronic acid in preserving functional independence in elderly pts with cancer-associated bone disease, the challenges involved in treatment are described, and the potential utility of bisphosphonates, such as zoledronic acid, is discussed.
Methods- Most elderly pts with metastatic cancer also suffer from numerous comorbidities.
- Management of bone health in this setting requires special consideration.
- This article centers on malignant bone disease in the elderly and the role of bisphosphonates in geriatric oncology.
- Recent data from several large clinical trials suggest that zoledronic acid provides additional benefits, including antitumor effects that may extend beyond the preservation of bone health and prevention of skeletal-related events.
Today in Bone/Cartilage...keeping you current
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Endoprosthetic proximal femur replacement: Metastatic versus primary tumors
Surgical Oncology, 11/05/09
Toxicity of Bisphosphonates
Journal of Palliative Medicine, 11/23/09
Survival in high-grade osteosarcoma: improvement over 21 years at a single institution
Annals of Oncology, 11/16/09
Today in Pharmacology/Therapy...keeping you current
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Activity of fulvestrant in HER2-overexpressing advanced breast cancer
Annals of Oncology, 11/06/09
Randomized phase II study of gemcitabine administered at a fixed dose rate or in combination with cisplatin, docetaxel, or irinotecan in patients with metastatic pancreatic cancer
Journal of Clinical Oncology, 11/02/09
Comparison of neurocognitive functioning in children previously randomly assigned to intrathecal methotrexate compared with triple intrathecal therapy for the treatment of childhood acute lymphoblastic leukemia
Journal of Clinical Oncology, 11/09/09
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