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See Latest ArticlesHypoxia-Inducible Factor-1 Suppresses Squamous Carcinogenic Progression and Epithelial-Mesenchymal Transition
Cancer Research, 03/30/09
Scortegagna M et al. - The authors discovered a novel HIF-1 target gene, selenium binding protein-1 (Selenbp1), a gene of unknown function whose expression is lost in human cancer. Thus, HIF-1 can function as a tumor suppressor through transactivation of genes that are themselves targets for negative selection in human cancers.
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Today in Basic Science/Genetics...keeping you current
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Thrombopoietin in normal and neoplastic stem cell development
Best Practice & Research: Clinical Haematology , 12/07/09
Mechanisms of mutations in myeloproliferative neoplasms
Best Practice & Research: Clinical Haematology , 12/07/09
Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma
International Journal of Cancer, 12/07/09
Today in Carcinogenesis...keeping you current
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Aggressive inherited and sporadic medullary thyroid carcinomas display similar oncogenic pathways
Endocrine-Related Cancer, 12/07/09
Activation of the hedgehog-signaling pathway in human cancer and the clinical implications
Oncogene, 11/30/09
Association of rare MSH6 variants with familial breast cancer
Breast Cancer Research and Treatment, 11/25/09
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