Oncology Medical News about osteosarcoma;incidence and survival

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Osteosarcoma incidence and survival rates from 1973 to 2004: Data from the Surveillance, Epidemiology, and End Results Program
Cancer, 02/18/09

Mirabello L et al. – A comprehensive, population-based description of osteosarcoma, identified important differences in incidence, survival, pathologic subtype, and anatomic site among age groups, and quantified the impact of osteosarcoma in pts with Paget disease or as a second cancer on incidence and mortality rates. These findings may have implications in understanding osteosarcoma biology and epidemiology.

Methods

Review of Surveillance, Epidemiology, and End Results (SEER) data 1973-2004 for frequency, incidence, and survival rates in 3,482 osteosarcoma pts
Analysis by age (0-24, 25-59, 60-85 yrs), race, sex, pathology subtype, stage, anatomic site

Results

Large differences in incidence and survival rates by age
High percentage of osteosarcoma with Paget disease and osteosarcoma as second or later cancer among elderly pts
High percentage of osteosarcoma among pts with Paget disease and osteosarcoma as a second or later cancer among elderly
Tumor site differences noted among age groups
Survival rates varied by anatomic site and disease stage and did not improve significantly from 1984 to 2004

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