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Eosinophilia-associated muscle disorders: an immunohistological study with tissue localisation of major basic protein in distinct clinicopathological forms
Journal of Clinical Pathology, 02/09/09

Cantarini L et al. - MBP immunohistology on skeletal muscle, previously performed only in acute eosinophilic polymyositis, suggests that eosinophil-mediated injury of muscle cells may occur in a wider spectrum of less aggressive eosinophilia-associated myopathies. As conventional histology is likely to underestimate this leukocyte subset, MBP stain might therefore be a tool in analysis of tissue infiltration of eosinophils, as a possible treatment target.

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