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See Latest ArticlesSpecific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells
Carcinogenesis, 01/30/09
Chatagnon A et al. - Results indicate that MBD2 is specifically and directly involved in the transcriptional repression of hTERT in HeLa cells. This specific transcriptional repression was also observed in breast, liver and neuroblastoma cancer cell lines. Thus, MBD2 seems to be a general repressor of hTERT in hTERT-methylated telomerase-positive cells.
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Today in Basic Science/Genetics...keeping you current
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Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer
Cancer Causes and Control, 12/03/09
A comprehensive analysis of common genetic variation in MUC1, MUC5AC, MUC6 genes and risk of stomach cancer
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Today in Carcinogenesis...keeping you current
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Targeted Inhibition of Mammalian Target of Rapamycin Signaling Inhibits Tumorigenesis of Colorectal Cancer
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