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See Latest ArticlesBase excision repair of oxidative DNA damage and association with cancer and aging
Carcinogenesis, 01/28/09
Maynard S et al. - The major mechanism that cells use to repair oxidative damage lesions, such as 8-hydroxyguanine, formamidopyrimidines, and 5-hydroxyuracil, is base excision repair (BER). The BER pathway in the nucleus is well elucidated. More recently, BER was shown to also exist in the mitochondria. Here, authors review the association of BER of oxidative DNA damage with aging, cancer and other diseas
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