Oncology Medical News about prostate cancer risk;vitamin and mineral use

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Vitamin and mineral use and risk of prostate cancer: the case-control surveillance study
Cancer Causes and Control, 12/29/08

Zhang Y et al. - In a trial to examine the relation of use of multivitamins as well as several single vitamin and mineral supplements to the risk of prostate cancer, it was found that long-term zinc intake from multivitamins or single supplements is associated with a doubling in risk of prostate cancer.

Methods

The relation of use of multivitamins and several single vitamin and mineral supplements to the risk of prostate cancer was examined among 1706 prostate cancer cases and 2404 matched controls using data from the hospital-based case–control surveillance study.
Odds ratios (OR) and 95% confidence intervals (CI) for risk of prostate cancer were estimated using conditional logistic regression model.

Results

For use of multivitamins that did not contain zinc, the multivariable odds ratios of prostate cancer were 0.6 for 1–4 yrs, 0.8 for 5–9 yrs, and 1.2 for 10 yrs or more, respectively.
Men who used zinc for 10 years or more, either in a multivitamin or as a supplement, had an approximately 2-fold increased risk of prostate cancer.
Vitamin E, beta-carotene, folate, and selenium use were not significantly associated with increased risk of prostate cancer.

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