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minimal deviation adenocarcinoma of the cervix; lobular endocervical glandular hyperplasia Article Summary

Print     Email This Article     Save in My Library   Free Abstract
Hashi A et al. – INCI presence is a good parameter for diagnosis of lobular endocervical glandular hyperplasia (LEGH); cytology is an effective aid in the differentiation of LEGH from minimal deviation adenocarcinoma (MDA)

Methods

  • Study of cytologic features of LEGH and MDA in 40 smears from 28 pts
  • Review of 24 cases of LEGH (18 pure and 6 mixed forms) and 4 MDA cases of the cervix

Results
  • Abundant yellow mucin frequent in both LEGH and MDA; INCI noted in 22 of 24 LEGH cases but not in either MDA or adenocarcinoma cells associated with LEGH
  • Neither cell atypia nor architectural distortion noted in LEGH
  • In MDA, slight cellular atypia, 3D, irregular cell clustering, and prominent nucleoli were noted

 

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