Hashi A et al. – INCI presence is a good parameter for diagnosis of lobular endocervical glandular hyperplasia (LEGH); cytology is an effective aid in the differentiation of LEGH from minimal deviation adenocarcinoma (MDA) Methods
Study of cytologic features of LEGH and MDA in 40 smears from 28 pts
Review of 24 cases of LEGH (18 pure and 6 mixed forms) and 4 MDA cases of the cervix
Results
Abundant yellow mucin frequent in both LEGH and MDA; INCI noted in 22 of 24 LEGH cases but not in either MDA or adenocarcinoma cells associated with LEGH
Neither cell atypia nor architectural distortion noted in LEGH
In MDA, slight cellular atypia, 3D, irregular cell clustering, and prominent nucleoli were noted