Sultana A et al. – Strongest trends on indirect comparison favor gemcitabine plus capecitabine or gemcitabine plus a platinum compound over gemcitabine plus irinotecan, and to a lesser degree, over gemcitabine plus 5-fluorouracil Methods
Assessment of randomized controlled trials of 4 gemcitabine-based combinations: gemcitabine plus a platinum compound or 5-fluorouracil or irinotecan or capecitabine
Use of the Bucher adjusted indirect comparison method
Results
No combination was significantly superior to another