Nusko G et al. - Metachronous adenomas show uniform characteristics as small tubular lesions rarely bearing high-grade dysplasia; regular surveillance may serve as sufficient prevention of colorectal carcinoma Methods
Study of long-term results of follow-up colonoscopy after polypectomy in pts of the Erlangen Registry of Colorectal Polyps of > more than 20,000 polyps prospectively documented between 1978-2003
Review of 1,091 pts undergoing periodic surveillance for differences between initial and metachronous lesions of the colorectum
Results
Metachronous adenomas are significantly smaller ones, more frequently tubular lesions, and less often bear high-grade dysplasia
Adenomas of advanced pathology are found significantly less often at follow-up vs baseline examination
These differences are noted between initial and 4 subsequent generations of metachronous adenomas
Pts with adenomas of advanced pathology at baseline have a significantly higher risk for metachronous adenomas of advanced pathology at the first recurrence
See all
