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Article Summary
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Zhao Y et al. – ZNRD1 may have an important role in esophageal carcinogenesis Methods- Immunohistochemical, RT-PCR, and real-time PCR analysis of ZNRD1 expression in esophageal cancer
Results- Cytoplasmic staining pattern consistent in all epithelial cells for ZNRD1 antibody
- ZNRD1 expression statistically correlated with differentiation, invasion depth, lymph node metastasis, pathologic stage, lymphatic and vascular invasion
- Survival rates statistically lower for pts with ZNRD1-negative vs -positive tumors
- ZNRD1 expression was downregulated in esophageal cancer tissues vs adjacent non-neoplastic tissues
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