Tsukamoto S et al. - In a study to examine the clinicopathological characteristics and prognosis of pts with rectal well-differentiated neuroendocrine tumors (W/D NETs) to clarify the oncological outcome, it was shown that because the incidence of lymph node metastasis is very high in pts with rectal W/D NETs greater than 10 mm in diameter, radical surgery is required. The outcome of rectal W/D NETs pts with lateral pelvic lymph node metastasis was better than expected Methods
23 pts who underwent surgical treatment with lymph node dissection for rectal W/D NETs were reviewed
Results
Median tumor size measured preoperatively was 13 mm, and the median number of dissected lymph nodes was 16
The incidence of lymph node metastasis was 61%
The smallest W/D NETs with lymph node metastasis was 10 mm in diameter
All pts without lymph node metastasis survived without recurrence
Among 11 pts who had only regional lymph node metastasis, only 1 developed liver metastasis and died 13 months after initial surgery
Among 3 pts with lateral pelvic lymph node metastasis, 2 survived more than 5 years, although 2 had liver metastasis
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