Bolenza C et al. – Radical nephroureterectomy (RNU) provides adequate local control and long-term disease-specific survival (DSS) in pts with localized upper tract urothelial carcinoma (UTUC); lymphovascular invasion (LVI) and pT stage are independent predictors for reduced DSS and may identify pts likely to benefit from adjuvant therapies Methods
Study of predictors of urothelial recurrence, distant metastases, and DSS after RNU for UTUC in 116 pts
Review of pt records and tumor specimens for pathologic tumor (pT) stage, grade, LVI, concomitant carcinoma in situ (CIS), and presence of significant tumor necrosis
Results
Median follow-up: 38 mo (range: 1-193 mo)
At actual follow-up, 63 pts (56%) were alive and disease-free
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