Turashvili G et al. – A possible association between columnar cell lesions (CCLs) and breast tissue composition, including mammographic density, is reported Methods
Study of possible association of CCLs with breast composition, particularly breast density, in non-tumor containing breast tissue
Review of randomly selected tissue samples from bilateral subcutaneous mastectomy from a forensic autopsy series assessing tissue composition
Review of H&E slides for atypical/nonatypical CCLs; correlation with histologic features on quantitative microscopy
Results
CCLs in 40 of 236 cases (17%)
CCLs associated with several tissue composition measures: radiographic density: high Faxitron Wolfe Density, high density estimated by percentage non-adipose area, high percentage collagen, and high percentage glandular area
DCIS in 2 atypical CCL cases
CCL extent not associated with any examined variables
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